Gingivitis essays

Gum disease articles In an ongoing report, it was found that more than seventy-five percent of Americans age thirty-five and more established have some type of gum ailment. The main phase of gum sickness is gum disease, which is a turmoil including aggravation of the gums. Gum disease is brought about by plaque, a film of microscopic organisms that covers the teeth. At the point when plaque solidifies, or calcifies, it transforms into a tartar, or analytics. Plaque and tartar develop and make pockets of microscopic organisms between the teeth and gums. It might bring about gums getting aroused or swollen. This can likewise cause seeping of the gums. Whenever left untreated, gum disease can advance to periodontitis, which is the second phase of gum infection and progressively genuine. Periodontal infection causes demolition of bone and structures supporting the teeth (www.umanitoba.ca/outreach/wisdomtooth/stagesof.htm). Normally, poor oral cleanliness is a typical hazard factor for being determined to have gum disease. In any case, different elements may add to this gum malady. Heredity is a typical factor prompting gum disease. Microorganisms might be more hurtful to certain people groups gums than others. Different meds cause dry mouth and lessen the purifying capacity of spit. This makes plaque and tartar develop all the more without any problem. Another reason prompting gum sickness is the utilization of tobacco. It eases back the mending procedure of gums making microscopic organisms pulverize tissue. Additionally, individuals with diabetes are at a more serious danger of building up a gum illness. Diabetes might cause thickening of veins, which makes it progressively hard to convey supplements to the gum tissue. Furthermore, pregnant ladies become increasingly inclined to impeding impacts of plaque and microorganisms as a result of hormonal changes during pregnancy (www.cnn.com/HEALTH/library/DS/00363.html). Individuals influenced by periodontal infection are likewise at a more serious danger of genuine ailments. Studies uncover there is a connection between microorganisms in the mouth and c ... <!

Synthesis of Isatin Based Caspase Inhibitors

Blend of Isatin Based Caspase Inhibitors Structure AND SYNTHESIS OF ISATIN BASED CASPASE INHIBITORS FOR RUTHENIUM CAGING APPLICATIONS KASUN CHINTHAKA RATNAYAKE Dynamic Apoptosis is the vitality subordinate customized cell passing. Ill-advised capacity of apoptosis could prompt infections, for example, tumors, strokes, alziemer’s ailment. Caspases are the compounds engaged with the later phase of this procedure. Peptidyl and non-peptidyl caspase inhibitors have been combined as of late. One of these non-peptidyl compound classes which comprise of pyrrolidinyl-5-sulfo isatins have demonstrated a more noteworthy power against killer caspases, caspase-3 and - 7. As indicated by writing and for additional confining investigations, two mixes were planned, integrated and assessed their restraint against caspase-3 in this examination. The simple where its N-1 position alkylated with a 4-methyl pyridine moiety (7) demonstrated a higher hindrance than the simple wherein its N-1 alkylated with cyanoethyl gathering (8). Accordingly, the compoundâ 7â was chose for additional confining examinations with ruthenium. Part 1: Introduction 1.1 Apoptosis and Caspases Apoptosis is the procedure of customized cell passing. This is a huge cell process which is legitimately co-related with embryogenesis, invulnerable framework, maturing and different ailments including malignancies, stroke, myocardial dead tissue and neurodegenerative disorders.1 Caspases (cysteinyl subordinate aspartate coordinated explicit proteases) are the chemicals associated with the later phase of apoptosis. Caspases are isolated to various classes as per their pretended in the flagging course of apoptosis. Caspases 6, 8, 9 and 10 are included as initiators and caspases 2, 3 and 7 are distinguished as killer caspases in the flagging cascade.2The caspases 1, 4 and 5 are seen as non-dynamic in the cell demise process. 1.2 Caspase hindrance and changed isatin sulfonamides as caspase inhibitors Caspases assume a noteworthy job in both aggravation and apoptosis. Broad inquires about have been directed on caspases and their capacities since they go about as potential focuses in medicate revelation. Different inhibitors of Caspase have been made. These inhibitors could be sorted as non-peptidyl and peptidyl based mixes. A more noteworthy selectivity could be accomplished when non-peptidyl inhibitors are utilized for various sorts of caspases. Isatin sulfonamides have demonstrated restraint on killer caspases (caspase-3 and - 7) in late examinations. In 2000, Lee and analysts revealed the x-beam structure of caspase-3 with an isatin simple, 1-methyl-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)- 1h-indole-2,3-dione (a) bound to the dynamic site of the protein (Figure 1).3 Modifying isatin sulfonamide analogs with pyrrolidine bunches have demonstrated critical impact on caspase inhibition.4 For instance, different pyrrolidinyl-5-sulfo isatins have been demonstrated restraint to caspases, 3 and 7 (Figure 2). These isatin sulfonamide analogs are altered utilizing structure movement connections and played out these organic examines. The accompanying isatin sulfonamides have demonstrated to be repress caspase-3. The stereochemistry of subbed pyrrolidine moiety, cyclic versus non-cyclic ring structures and ring sizes have been inspected for these restraint contemplates (figure 3).5 1.3 Ruthenium buildings for confining applications Ruthenium mixes have been accounted for as noteworthy contender for confining applications. Light initiation of these metal edifices has been broadly examined. As of late, neuroactive biomolecules just as little atomic protein inhibitors have been accounted for to be confined with these ruthenium buildings. Spatial and worldly arrival of these confined atoms upon light actuation offers understanding to grow new devices that could be utilized to treat different maladies in organic frameworks. In this investigation Ruthenium polypyridyl mixes are utilized in future examinations since they have been considered as astounding possibility for confining utilization of little particles. Part 2: Results and Data 2.1 General contemplations All reagents were bought from business providers and utilized as got. Varian FT-NMR Mercury-400 Spectrometer was utilized to record all NMR spectra. IR spectra were recorded on High goals mass spectra were recorded on.Melting focuses were recorded on .Enzyme restraint examines were done on 2.2 Designing of Caspase inhibitors Late examinations show that different 5-pyrrolidinylsulfonyl isatins go about as caspase-3 inhibitors. A few components were considered in the structuring procedure of these analogs. To begin with, higher caspase hindrance was thought of. Utilization of explicit stereochemistry in the pyrrolidine moiety is significant since S-alkoxypyrrolidine is more strong than its R-stereoisomer which shows basically no intensity against caspase-3. It is accounted for that methoxymethyl pyrrolidinyl analogs show higher cell harmfulness than phenoxymethyl pyrrolidines, subsequently methoxymethyl pyrrolidine analogs were picked for additional investigations. While considering the Ruthenium confining examinations, the picked analogs ought to contain a gathering which has a higher restricting affinitiy towards Ruthenium. Accordingly, pyridyl and cyano bunches were chosen to consolidate in these isatin sulfonamide analogs. These gatherings are picked to be connected to N-1 situation of isatin sulfonami de simple. It has been accounted for that higher alkyl chain on N-1 position could build the hindrance. Subsequently 4-methylpyridine and cyanoethyl bunches were chosen to join on N-1 situation of these analogs and mixes 7 and 8 are structured (Figure 3). 2.3 Synthesis of planned isatin sulfonamide analogs The planned analogs were integrated utilizing writing and adjusted procedures5, 6, 7 (Scheme 1). The compound 5 was integrated as the antecedent for the last analogs 7 and 8. The mixes 7 and 8 were blended utilizing altered and advanced methods (Scheme 2 and Scheme 3). 2.4 Enzyme Inhibition Assay Caspase-3 hindrance examine was performed for mixes 6 and 7 as indicated by the writing procedure.2 Compound 6 was seen as increasingly strong (IC50 = .. ) of than compound 7 (IC50 = ..). In this manner, compound 6 was chosen for additional confining investigations with Ruthenium bipyridine edifices. 2.5 Experimental 2.5.1 Sodium 2,3-dioxoindoline-5-sulfonate (1) Isatin (10 g, 0.068 mol) was added cautiously to a mixed arrangement of 20% SO3/H2SO4 (20 mL) at - 15Â °C. The response blend was tenderly heated up to 70 Â °C with mixing. Response blend was mixed at 70 Â °C for another 15-20 min. The response blend was painstakingly poured on to squashed ice and let ice to dissolve and afterward 20% NaOH was added to the response blend (pH=7). The jar containing response blend was kept in an ice shower to incite precipitation of the ideal item. The strong was separated, washed with super cold water and dried to give red-orange crystalline strong. The 1H-NMR information was contrasted and coordinated and writing information. Yield: 14.48 g (0.051 mol. 75%) 2.5.2 2,3-dioxoindoline-5-sulfonyl chloride (2) Sodium 2,3-dioxoindoline-5-sulfonate dihydrate (2 g, 70 mmol) was broken up in tetramethylene sulfone (10 mL) under Argon condition at 60-70 Â °C and phosphorus oxychloride (3.36 mL, ) was included dropwise. The response blend was mixed for 3 h. The response was cooled to room temperature and kept in an ice shower. At that point super cold water was added to the response blend cautiously. An accelerate was framed, separated, washed with super cold water and dried utilized moving along without any more cleaning. The ideal compound is yielded as a brilliant yellow strong. The 1H-NMR information was contrasted and coordinated and writing information. Yield: 1.58 g (64 mmol, 92%). 2.5.3 Tert-butyl (S)- 2-(methoxymethyl)pyrrolidine-1-carboxylate (3) To an answer of N-Boc-L-prolinol (5.0 g, 25 mmol) in THF (25 mL) at - 78 Â °C, Sodium hydride (60% in mineral oil) (960 mg, 40.0 mmol) was included and mixed for 10 min. At that point methyl iodide (2.65 mL, 42.5 mmol) was included dropwise and response was mixed for 4h at - 78 Â °C and extra 16 h at RT. At that point NH4Cl was included until all H2 developed and EtOAc was included. The natural layer was washed with water and sat. NaCl, dried over anhyd. Na2SO4 and concentrated to give a light yellow oil and cleansed with oil ether: ether (9:1) to give a dreary oil. The 1H-NMR information was contrasted and coordinated and writing information. Yield: 4.986 g (23.16 mmol, 92%) 2.5.4 (S)- 2-(methoxymethyl)pyrrolidine (4) To an answer of tert-butyl (S)- 2-(methoxymethyl)pyrrolidine-1-carboxylate (4.98 g, 23.07 mmol) in DCM (40 mL), TFA (25 mL) was included dropwise more than 30 min at 0 Â °C. The response was warmed to RT and mixed for extra 1.5 h. The response blend was added to 150 mL of 10% NaOH arrangement and separated with DCM (50 mL x 3), dried over anhyd. Na2SO4 and concentrated to get a light yellow oil. The 1H-NMR information was contrasted and coordinated and writing information. Yield: 2.657 g (23.07 mmol, 100%) 2.5.5 (S)- 5-((2-(methoxymethyl)pyrrolidin-1-yl)sulfonyl)indoline-2,3-dione (5) The compound (1) was combined by method detailed by Harvan et al.1 To a blended arrangement of 2,3-dioxoindoline-5-sulfonyl chloride (2 g, 8.153 mmol) in 1:1 THF/CHCl3 (80 mL), an answer of (S)- 2-(methoxymethyl)pyrrolidine (1.033 g, 8.968 mmol) and DIPEA (2.84 mL, 16.310 mmol) in CHCl3 was included dropwise under Argon condition and mixed for 1 h at 0 Â °C. The response mixed for extra 1 h at RT. The response blend was thought and refined utilizing 1:1 EtOAc:Petroleum ether and disengaged as brilliant yellow precious stones. The 1H-NMR information was contrasted and coordinated and writing information. Yield: 1.185 g (36.53 mmol, 45%) 2.5.6 4-(bromomethyl)pyridine hydrobromide salt (6) Pyridin-4-ylmethanol (5.0 g) was broken down in 48% HBr (50 mL) and refluxed for 24 h. (Response was observed for finishing utilizing TLC). The response blend was packed in vacuo until a thick gum showed up and treated with outright Ethanol at 5 Â °C. The white crystalline strong got was

Finding My Way Around MIT (Guest Entry)

Finding My Way Around MIT (Guest Entry) by Rena Katz CPW was so hugely difficult to take in all at once that its hard to sum it all up in one blog post, much like its hard to condense your life into 500 words for the admissions office. But I shall try. I arrived at CPW on Friday morning and went to the opening lecture. Amy Smith gave an excellent presentation about some of the challenges of living in developing countries and how people could help. She talked about tools and devices that were redesigned to be inexpensive enough for people to afford. A major challenge for many people is finding fuel, usually wood, which smokes and leads to disease. Ms. Smith and her team developed a method of producing charcoal bricks out of natural waste materials in the communities that needed fuel. She works with students on projects that really do help people, which I think is a fantastic thing to be involved in. For lunch on Friday, I met my awesome friend Daniel and a new friend named Rebecca. We sat in on a geology class which had videos of lava flowing, exploding, and making pillows and streams. After getting some free food, we sat in on a 8.02 class (Electricity and Magnetism physics). It had PowerPoint slides on screens all over the room, and the professor could ask questions for the students to answer with clicker remotes, which is what makes it a TEAL (Technology-Enabled Active Learning) class. Im not sure if the TEAL would help me learn better, but its an interesting idea. We got to see sparks. Lots of them. Big ones. The best demonstration was a giant switch connected to a giant inductor. A volunteer closed the switch, but nothing happened. You could practically see that inductor snickering to itself, just waiting. When the student opened the switch, there was a HUGE green spark. The student just sat there like he sees huge random green sparks every day who knows? Maybe he does. Th e inductor was a little disappointed that no one ran screaming out of the room. I also saw Snively, but he disappeared before I could say hi. Bouncy balls. Falling from the sky. What more can be said? I guess we showed up too late for Meet the Bloggers, since there werent many people left. I got to talk to Ben Jones, who is more awesome in person, if thats possible. I thanked him for setting up such a great admissions process/website/blogs. I really feel that MIT cares about its prefrosh and wants to help as much as possible, and I appreciate that very much. Thanks to all the admissions officers! I stayed in a suite in Burton 5. My host Sara and her suitemates were very nice. I even got to sleep in a bed instead of the floor I was expecting. My absolute favorite view near Boston is the multicolored lights of Boston reflected in the Charles River at night, especially if you are high enough so the buildings dont get in the way. We were going to go see Baker House, but we ended up at East Campus, where they were telling stories of some of the hacks that MIT has done over the years. Luckily, we saw no zombies, but we would have been well prepared thanks to the chainsaw hack that Snively and prefrosh already blogged. Random Hall had pancakes at 2:17 in the morning. In fact, they had lots of, well, random activities at :17 past the hour. Seventeen is supposed to be the most random number because people will pick 17 most often when they choose a random number between 1 and 20. Random Halls funniest activity was a nerf gun war. They set up the couches to make forts so ten people could fire foam darts at each other, which we did with much drama and laughter. The practical people would crouch behind the couches and wait, and the more daring would leap over to the other side and try to shoot people before they could reload their guns. It was even more funny when the guns didnt work. Best quote of the night: You shouldnt remember from this that MIT is awesome, but that I am awesome. When I got to MIT, I felt like a prefrosh, probably because I am one. I had a sleeping bag, very little idea where to go, and I didnt know anyone. On the morning that I left MIT, I had a geeky sweatshirt, I knew my way around campus, and I could hardly tell who was a prefrosh and who was a student. CPW assimilates prefrosh into MIT culture. On the first day, I was an it, a prefrosh, a visitor. When I left, people knew my name. I had random conversations all weekend. Everywhere, every time, there was always someone who would say hello, whether it was 8:30 AM in the student center or 8 PM at Battle of the Bands or 2 AM at Random Hall. I dont like everything about MIT, but thats because there is so much diversity in the people, the living groups, and the activities. Im confident that I can find a niche where I fit in. It was a great feeling to eat breakfast before leaving on Sunday and realize that Ill be back in Cambridge in the fall.

Poverty Influences Children s Early Brain Development

Poverty Influences Children’s Early Brain Development Children have been the topic of many research studies and debates throughout history. Scientists, educators, social workers and teachers have debated the importance of nature and nurture in children s development. Our ideas of children are shaped greatly by the portrayal of children through media. Producers, journalists, and writers have the power to either portray children as passive or active agents in their development of social, academic and life skills. The authors’ assumptions and personal beliefs of children or childhood can be identified through the way they represent children in their writings. In the article, â€Å"Poverty Influences Children’s Early Brain Development† the author reports the effect that poverty has on the development of infants and young children’s brain size. Developing children are portrayed as passive, relying on the guidance of parents, caretakers and the community, rather than being seen as active agents who can utilize an innate ability to learn, and overcome any obstacles, including poverty. The author focuses on the idea that children, while developing, are dependent on stimulation from others: parents, relatives, caregivers and the environment to learn socio-emotional skills that impact their ability to learn in the future. The author’s perspective of children as passive beings can be inferred from his selection of quotes included in his article. For example, in the newsShow MoreRelatedHuman Brain Development1231 Words   |  5 PagesChildren begin learning before they are even born. Some people may wonder how this is possible if the child hasn’t even taken its first breath yet, but it is true. Brain development begins in week four of their first trimester in the womb. This is important because the development helps a child learn and grow, effecting their future learning, education, and social skills. Brain development begins right in the womb and continues to flourish after birth. A child’s brain develops through neurons andRead MoreLifespan Development1516 Words   |  7 PagesLifespan Development and Personality Luis Cervantes PSY/103 January 11, 2016 Susanne Nishino Lifespan Development and Personality Developmental psychology is the study of how human beings age and transform throughout the eight major stages of life. This paper will focus on the physical, cognitive, social, moral, and personality development of individuals found in stage two, (early childhood 1-6 year olds). Through exploring, and examining the countless influences that affect their growthRead MoreIndividual Diffferences - How environmental factors affect Personality Intelligence1525 Words   |  7 Pagescan impact on the development of an individual’s personality and intelligence. The discussion in this essay entails the extent to which environmental factors impact an individual’s development of personality and intelligence. Development can be defined as ‘improvement in function’ which would imply that it occurs with the progression of age. Personality has been found to have a substantial genetic influence however economic and social factors have been found to effect the development of personalityRead MoreThe Importance Of Childhood Experiences Of Children And The Social And Economic Benefits Of Early Intervention1553 Words   |  7 Pageschildhood experience to later life emotional, social and cognitive development into adulthood in the Uk, using the attachment and behaviorism theory to examine childhood experiences, as it forms parts of child’s development. I will be looking into the factors affecting social, emotional and cognitive development of children, strategies to improving service delivery of early intervention in children and the Social and economic benefits of early intervention. Attachment theory is a concept in developmentalRead MoreLearning Styles And Sociocultural Influences On Child And Adolescent Development1641 Words   |  7 Pagesmedia and will examine the link to development theories, learning styles and sociocultural influences on child and adolescent development. As a developing secondary school preserve teacher, my focus will be mainly on adolescent behaviours and development. I will be examining an article from a media how these developmental theories analyses and helps us to understand the behaviour of child and adolescents. I will also try to explain about the domain of development such as physical, cognitive, emotionalRead MoreThe Significance Of Child Development In Low Socioeconomic1517 Words   |  7 PagesSignificance of Child Development in Low Socioeconomic Communities Emma Kennedy Project #1 AIS 1203.027 University of Texas at San Antonio Introduction Poverty creates long term disadvantages for children. Many of these disadvantages include lower academic achievement, home environment stress, and relational issues between parent and child. In our world today, poverty is affecting more children developmentally. It has been accounted as of 2017, that 15 million children in the UnitedRead MoreBackground Of Kindergarten Education And Children s Psychology975 Words   |  4 PagesReview of Literature Background of Kindergarten Education and Children s Psychology Learning is developmental: Children, and their brains, benefit from enriched home and school environments (Connell, 2009) According to the Piaget’s research those children having four main stages of mental development. First stage, it is sensory motor intelligence to cover brain in the first and two years of children’s life. For this time, children know the world through their perceptions ability, such as they knowRead More Adolescence and Juvenile Delinquency Essay1644 Words   |  7 Pagessummed up juvenile delinquency best with this definition; resistant antisocial, illegal, or criminal behavior by children or adolescents to the degree that it cannot be controlled or corrected by the parents, endangers others in the community, and becomes the concern of a law enforcement agency(1994). I found that most theories about what causes delinquency in children and adolescents originate with families and parenting. Many statistics and studies have been conducted comparingRead MoreEffects Of Low Socioeconomic Status On Mental Health1440 Words   |  6 Pages Enormous amounts of research have linked socioeconomic status to mental health, especially in children and adolescents. Low poverty levels have been specifically identified as a key causal factor in developing mental health problems in children. There has been much discussion over the different theories as to why this is the case, but only two of these theories seem to hold a lot of evidence. Certain interventions and preventative measures can be employed in order to improve an individual’s mentalRead MoreEarly Childhood : Childhood Development1494 Words   |  6 PagesENG-5062 Due date:9 august 2017 Early childhood development Early childhood is the the time period when a child opens his eyes in the world and it continues upto the age of 8 years old (Masten et al. â€Å"NAME OF ARTICLE†)This is really the time in which the brain of the child starts growing and basis for the subsequences of development. Early childhood period starts at home the very first stages of life. Parents have a great role in childhood development. Then the second factor or place which

Review Of The New Yorker Essay - 1892 Words

Thirteen year old Megan Meier befriended and began exchanging messages with someone who she thought was a cute 16 year old boy named Josh Evans on Myspace. The messages from Josh started out complimentary but quickly became hostile, soon leading to other forms of cyberbullying. Meier, already struggling with depression, grew even more depressed as the online harassment continued. On October 16, 2006, Meier hanged herself in her bedroom closet, dying a day later. Soon after, news surfaced that the â€Å"Josh Evans† Meier had been communicating with was not an actual person, but simply a fake account. A mother in Meier’s neighborhood ran the account, claiming that she made it in order to ascertain how Meier felt and what Meier was saying about her daughter. Due largely in part to a mother’s deep entrenchment in her daughter’s personal life, Megan Meier committed suicide, serving as an extreme example of the dangers of an overbearing parent. George Saundersâ €™s 2009 short story first published in The New Yorker (later republished in his 2013 collection of short stories The Tenth of December: stories) also relays the dangers of overbearing parenting, but in a more direct manner. In the story, Kyle Boot—whose entire life is dictated and organized by his overbearing, overprotective parents—saves Alison Pope from a man who attempted to kidnap her by bludgeoning the assailant with a geode. As he does so, his mind splinters into an excessively violent, yet independent, entity. â€Å"Victory Lap†Show MoreRelatedComparing Penelope And The Suitors956 Words   |  4 Pages22, 1893 in West End, New Jersey. She worked on such magazines as Vogue and Vanity Fair during the late 1910s. During the 1920s, Dorothy Parker became famous by writing book reviews, poetry, and short fiction for fledgling magazine The New Yorker. Parker went on to work as a book reviewer for The New Yorker in the 1920s. A selection of her reviews for this magazine was published in 1970 as Constant Reader, the title of her column. She remained a contributor to The New Yorker for many years; the magazineRead MoreAnalysis Of White And The New Yorker801 Words   |  4 PagesFurth ermore, In Warshow’s review of E.B White and the New Yorker, experience again is at the forefront of his critique, along with a bit of his ever present political views. He makes a very important point at the begging of this review, â€Å"The New Yorker has always dealt with experience not by trying to understand it but by prescribing the attitude to be adopted toward it.† (warshow 2001, 75) This becomes an interesting argument, even today, as we think about what trends we have seen in popular cultureRead MoreEssay on One Hundred Years of Solitude858 Words   |  4 Pagesthe New Yorker. The Power of Garcà ­a Mà ¡rquez Ââ€" A New Yorker article from September 1999. Shipwrecked Ââ€" Garcà ­a Mà ¡rquez New York Times op-ed piece on Elià ¡n Gonzà ¡lez. Love in the Time of Cholera Film Ââ€" July 22, 2004, The Guardian. Stone Village has acquired the film rights to film Garcà ­a Mà ¡rquezs novel of long-delayed love. In the Shadow of the Patriarch Ââ€" Nov. 2, 2003, New York Times Magazine. Francisco Goldman on Garcà ­a Mà ¡rquez. Solitude Company Ââ€" Summer 2003, Paris Review. SilvanaRead More Essay on One Hundred Years of solitude869 Words   |  4 Pagesin the New Yorker. The Power of Garcà ­a Mà ¡rquez – A New Yorker article from September 1999. Shipwrecked – Garcà ­a Mà ¡rquez’ New York Times op-ed piece on Elià ¡n Gonzà ¡lez. Love in the Time of Cholera Film – July 22, 2004, The Guardian. Stone Village has acquired the film rights to film Garcà ­a Mà ¡rquez’s novel of long-delayed love. In the Shadow of the Patriarch – Nov. 2, 2003, New York Times Magazine. Francisco Goldman on Garcà ­a Mà ¡rquez. Solitude amp; Company – Summer 2003, Paris Review. SilvanaRead MoreSummary Of Colum Mccann s The Great World 1097 Words   |  5 PagesIt is a seemingly ordinary August day in New York City in 1974. The city plays its everyday soundtrack of lumbering garbage trucks, screeching subway breaks, bustling people, and beeping taxicab horns. A diverse mix of people silently stares up in awe at the figure on the edge of a Twin Tower. â€Å"A dark toy against the cloudy sky† (1) runs, jumps, dances, and performs across a tightrope strung over 100 stories high in the sky. Let the Great World Spin, a masterpiece of a novel by renowned author, ColumRead More Biography of Ogden Nash Essay815 Words   |  4 Pages Ogden Nash was born on August 19, 1902 in Rye, New York and was raised there and in Savannah, Georgia. He received his education from St. George’s School in Rhode Island and he also attended Harvard University. His first published poem Spring Comes to Murray Hill was featured in the New Yorker Magazine in 1930. He subsequently joined the staff of the New Yorker Magazine in 1932. Throughout his career he published a total of nineteen books of poetry before his deathRead MorePrivacy Is A Fundamental Value Of Human Right1098 Words   |  5 Pagesdetermine what information is to be taken from him or her, to restrain exploitation. The government may say that the accessing of data is for the prevention of terrorist threats and greater safety. Director of NSA, General Keith Alexander interviewed by New York Times said that The agency is under rules preventing it from investigating that so-called haystack of data unless it has a reasonable, articulable justification, involvin g communications with terrorists abroad, Has our defense departmentRead MoreMy Experience At The Twin Towers Essay1098 Words   |  5 Pagesdevastation and just watched the towers fall. c. Introduce topic: d. Credibility statement: I have lived in New York my whole life. I live approximately 35 minutes from ground zero. My Grandfather was a helping hand in building the twin towers. My father was in the city the day the towers fell; he was safe but was unable to get home because all transportation was shut down. e. Thesis: The tragedy New York City experienced on September 11th, 2001 will forever be memorable to my community and I. It broughtRead MoreThe New York City Police Department Essay1723 Words   |  7 Pagesthe 1990s, the growth of violent crime reached its all-time high in New York City. In response to the number of high murder rates in the 1990s, the New York City Police Department realized that their efforts to reduce crime were ineffective. The local news reported that New Yorkers were afraid to wear their jewelry in public. Some reported they had to sprint to the subway exit to avoid victimization when the door opened. The New York City Police Department decided to implement a practice of StopRead MoreNew York State Housing Finance Agency Essay1046 Words   |  5 PagesBackground The New York State Housing Finance Agency (HFA) was formed in 1960, to assist low- and moderate-income family unit charter expansion (â€Å"New York State Housing Finance Agency†, 2012). In this logic its solemn assignment consists of preserving and conserving â€Å"high quality† low-priced rental housing for the population athwart the State of New York. Additionally, HFA provides financing to not-for-profit, and for-profit to construct economical letting houses, including NYCHA, and Mitchell Lama

Management Questions and Answers for Midterm Examination Free Essays

Identify and describe the three levels of the organizational hierarchy. Which types of Information systems serve each level? Answer: The three levels of the organizational hierarchy: Senior Managers Middle Managers Operational Managers Types of Information systems serve each level: Operational-level systems: support operational mangers, keeping track of the elementary activities and transactions. Management-level systems: serve the monitoring, controlling, decision-making, and administrative activities of middle managers. We will write a custom essay sample on Management: Questions and Answers for Midterm Examination or any similar topic only for you Order Now Strategic-level systems: help senior management tackle and address strategic issues. 2- List and briefly describe the major types of system in organization? Answer: Transaction Processing Systems (TIPS): are the basic business systems that serve the operational level of the organization. And it is also a computerized system that performs and records the daily routine transactions necessary to conduct business. Management Information Systems (MIS): serve the management level of the organization, providing managers with reports and often-online access to the organization’s current performance and historical records and primarily serve the functions of planning, controlling, and decision-making. Decision-support System (ADS): also serve the management level or the organization. ADS help mangers make decisions that are unique, rapidly changing, and not easily specified in advance. MIS differ from SEES: MIS serve at management level and SEES serve at strategic level. 5- What are the characteristics for ADS? How do they differ from those of SEES? Answer: Characteristics for ADS: (Inputs: transaction level data; Processing: Interactive; Outputs: Decision analysis; Users: Professional and staff ADS differ from SEES: ADS revere at management level and SEES serve at strategic level and its characteristics are: Inputs: Aggregate data; Outputs: projections; Users: senior managers. – Describe the relationship between TIPS, MIS, and SEES. The relationship between TIPS, MIS, and SEES: TIPS are typically a major source of data for other systems, data also be exchanged to MIS to produce reports, whereas SEES are primarily a recipient of date from lower-level systems. 7- List and describe the information systems serving each of the major functional areas of a business. Answer: Sale and Marketing Systems: System Description Organizational Level Order processing Enter, process, and track orders Operational Pricing analysis Determine prices for products and services Management Sale and forecasting Prepare 5 years sales forecasts Strategic Manufacturing and Production Systems Machine control Control the actions of machines and equipment Production planning Facilities location Decide where to locate new production facilities. Finance Accounting Systems Account Receivable Tracks money owed the firm Budgeting Prepares short-term budgets Profit planning Plans long-term profits Human Resource Systems Training and Development Tracks employee training, skills, and performance appraisals Operational Compensation analysis Monitors the rang and distribution of employee wages, salaries, and benefits Human Resource planning Plans the long-term labor force needs of the organization 8- What is a business process? Give two examples of processes for functional areas of the business and one example of a cross functional process. Answer: Business process refer to sets of logically related activities for accomplishing a specific business result, and also refer to the unique ways in which organization and management coordinate these activities. Example for functional area of business process: (Finance and Accounting: paying creditors, creating financial statements and managing cash accounts); (Human Resources: hiring employees, evaluating employees’ Job performance and enrolling employees in benefits plans) Example of a cross functional process: Order fulfillment process (Sales Department: Generate order and submit order; Accounting Department: Check credit and approve credit and then Manufacturing Production department: Assemble product and ship product, and finally Accounting Department: Generate invoice). Why are enterprise applications for organization-wide process integration? Answer: Organizations are trying to integrate their business processes because they want to enhance the performance of the organizations as a whole. The system takes advantage of corporate intranets and web technologies that enable the efficient transfer of information within the firm and to partner firms. And these systems are inherently cross-level, cross-functional, and business process oriented. The four key enterprise applications: Enterprise Systems, Supply Chain Management Systems, Customer Relationship Management Systems, and Knowledge Management Systems. 10- What are enterprise systems? How do they change the way an organization work? Enterprise Systems, also known as enterprise resource planning systems, provide a single information system for organization-wide coordination and integration of key business processes. Information that was previously fragmented in different systems can seamlessly flow throughout the firm so that it can be shared by business processes in manufacturing, accounting, human resources, and other areas. How to cite Management: Questions and Answers for Midterm Examination, Papers

Compare the representation of family relationships Essay Example For Students

Compare the representation of family relationships Essay This suggests that as a child, Hamlet may have greatly resented having to share his mother with his father, wanted undisputed priority in her life. This would then have led to repressed desires to sexually posses his mother, and ultimately eliminate his father. For Hamlet, his father has already been killed by the start of the play. However there is still no chance for him to be able to now take the coveted position in his mothers life that he desires. Adding insult to injury is the fact that it is now his own fathers brother who had married his mother and filled the void. It is easy to see how this twisted scenario would create a confused state of mind, even regardless of the Oedipus Complex. The incest that therefore penetrates this family is key to Hamlets frustration. He see the relationship between Claudius and Gertrude as incestuous, indeed the ghost of King Hamlet calls Claudius that incestuous, that adulterate beast. Hamlet is likely to feel a desire to avenge his fathers death, and possibly also jealousy towards Claudius. An interesting scene is Act 3 Scene 3 where the ghost appears to prevent Hamlet from causing further agony to his mother. Or is it possible that he appeared to prevent his son from taking his wife? This scene also serves to show us that Hamlet does indeed idolise his father. When talking to his mother he likens him to Hyperion, Mercury, and Mars, assigning him qualities of leadership, grace and the traits of a true warrior. To him, his father is Blasting his wholesome brother (line 66). This loyalty for his father partly fuels his need to kill Claudius but his enduring procrastination shows something is not allowing him to do it easily. Contrasted with Laertes, whose father has also been wrongfully murdered, we can see that he has no such delay in avenging his father. The telling difference may be that Laertes has no mother figure in his life. The reason could therefore be, that Hamlet may realise on a sub-conscious level that he actually needs Claudius in his mothers life to prevent his own incest with her. On another level, Laertes feels that to delay revenge would be to claim himself illegitimate. Unlike Hamlet he has no fears that he may be a bastard, a concept which consumes Hamlets mind. The issue of fatherhood in the play is also an important one Hamlets father is obviously an absent figure, but he still strives to be his son. Although all he has of his father is memories, he constantly tries to resurrect him with words and images. In the opening scenes it becomes clear that Claudius now comfortable sits in his brothers old position, in every sense except that which allows him to be a father to Hamlet. He attempts to push his way into Hamlets life in the beginning, saying But now, my cousin Hamlet, and my son to which Hamlet sneers A little more than kin and less than kind. Hamlet needs to protect his father to assert his roots and masculinity, and therefore must kill this impostor father figure trying to replace him. This involves deciding between the two fathers, and this is not so easy for him as it would seem. King Hamlet is Hamlets link to an honourable, legitimate past. It is the only way he can find his place in the world with dignity. To fail to support his father would be accept Claudius and therefore the illegitimacy and deceit which come with him. .ue4c8a68450054f32f0a2eb5e2c59dcbf , .ue4c8a68450054f32f0a2eb5e2c59dcbf .postImageUrl , .ue4c8a68450054f32f0a2eb5e2c59dcbf .centered-text-area { min-height: 80px; position: relative; } .ue4c8a68450054f32f0a2eb5e2c59dcbf , .ue4c8a68450054f32f0a2eb5e2c59dcbf:hover , .ue4c8a68450054f32f0a2eb5e2c59dcbf:visited , .ue4c8a68450054f32f0a2eb5e2c59dcbf:active { border:0!important; } .ue4c8a68450054f32f0a2eb5e2c59dcbf .clearfix:after { content: ""; display: table; clear: both; } .ue4c8a68450054f32f0a2eb5e2c59dcbf { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .ue4c8a68450054f32f0a2eb5e2c59dcbf:active , .ue4c8a68450054f32f0a2eb5e2c59dcbf:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .ue4c8a68450054f32f0a2eb5e2c59dcbf .centered-text-area { width: 100%; position: relative ; } .ue4c8a68450054f32f0a2eb5e2c59dcbf .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .ue4c8a68450054f32f0a2eb5e2c59dcbf .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .ue4c8a68450054f32f0a2eb5e2c59dcbf .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .ue4c8a68450054f32f0a2eb5e2c59dcbf:hover .ctaButton { background-color: #34495E!important; } .ue4c8a68450054f32f0a2eb5e2c59dcbf .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .ue4c8a68450054f32f0a2eb5e2c59dcbf .ue4c8a68450054f32f0a2eb5e2c59dcbf-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .ue4c8a68450054f32f0a2eb5e2c59dcbf:after { content: ""; display: block; clear: both; } READ: The themes of love and loss in the poems "My Last Duchess", "Shall I compare thee", "Let me not" and "Porphyria's Lover" EssayThe statement which Hamlet makes, father and mother is man and wife, man and wife is one flesh (Act 4, Scene 3, Lines 53-54) is quite telling of his fears of their sexual relationship, but perhaps he also recognises that at present Claudius fills this position of his mothers husband and must be given due respect. It is Hamlets blurred notions of female sexuality from which flow a central theme in the play. Janet Adelman discusses the concept that the maternal womb is contaminated by sexuality, and is a devouring and suffocating presence. The symbolism of an empty womb may be synonymous for Hamlet with sexual acts, and may also threaten to force him to return to it. Throughout the play Hamlet struggles to escape from the maternal influence. Gertrude herself is not actually portrayed as particularly wicked or powerful, but it is her inaction to prevent the chain of events spiralling from her husbands death which cause Hamlet to think of her as such. This causes more problems for the disturbed Hamlet as he feels that his own body has been sullied by his mothers actions. He fears the contamination will spread to him, and this causes his rash and panicked actions. He is sure that id female sexuality is polluted and incestuous, he can no longer be certain of who he is, and certainly whose son he is. This conception of the Bastard child corresponds to A Modest Proposal. The narrator created by Swift also accepts the problem of the bastard child and feels that it is easier to kill (and eat) the child rather than marry the parents. An idea very prominent in Hamlets own mind when he says To be or not to be, showing he has thoughts of ending his life. Swift seems to promote to some extent the usefulness of children with no certain father, but limits this at being able to kill and eat them more easily. He encourages males to have children by numerous partners, anticipating none of the problems which Hamlet is experiencing to arise in Ireland. A very relevant difference between A Modest Proposal and Hamlet is the class difference. Marriage is essential in the higher nobility, such as Hamlet is involved in, and although affairs were obviously commonplace, they were much little discussed. In the lower classes marriage was not so essential to status, as they had little to start with, and so it was often disregarded. However this seemed not to have made much difference to the actual happiness of either situation presented. Swift, like Shakespeare, blurs the roles of members within the family, and shows us the importance of every part, and relationship functioning. Swift also writes A Modest Proposal as a warning to the Irish lower classes to protect their own, and the shocking consequences which may occur if they ignore him.